Preimplantation genetic Testing for Aneuploidy (PGT-A) has been used in an attempt to determine embryonic aneuploidy. Transferring of aneuploid embryos leads to universally undesired outcomes such as failed embryo implantation, miscarriage or birth of trisomic offspring. Therefore, in each IVF cycle, it is really important and critical to make a well-informed decision regarding which embryo(s) to transfer.
Nextgen Genetics is offering advanced Preimplantation genetic Testing for Aneuploidy (PGT-A) with the cutting edge latest NGS (next generation sequencing) with proprietary algorithm to make the most accurate calls not only complete gain and loses but also for mosaic embryos. The primary advantage of NGS is the ability to simultaneously detect aneuploidies, deletions, duplications and unbalanced translocations. NGS uses thousands of small segments of DNA as a target for each chromosomes for analysis.
Nextgen Genetics has performed extensive validation with known karyotyped cells to produce high level of accuracy, reproducibility, sensitivity and specificity.